Six questions about the hygiene hypothesis

被引:34
作者
Bach, JF [1 ]
机构
[1] Hop Necker Enfants Malad, Serv Immunol, Paris, France
关键词
autoimmunity; infections; hygiene; diabetes;
D O I
10.1016/j.cellimm.2005.04.006
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
According to the hygiene hypothesis, the increased incidence of allergic and autoimmune diseases in developed countries is explained by the decrease in infections. Several questions remain unsettled, concerning notably the nature of protective infections, the mechanisms of protection, the spectrum of diseases concerned by the hypothesis, the difference between triggering and protective infections and lastly the strategies which could be devised to mimic the effect of infections. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:158 / 161
页数:4
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