Six questions about the hygiene hypothesis

被引：34

作者：

Bach, JF ^{[1
]}

机构：

[1] Hop Necker Enfants Malad, Serv Immunol, Paris, France

来源：

CELLULAR IMMUNOLOGY | 2005年 / 233卷 / 02期

关键词：

autoimmunity; infections; hygiene; diabetes;

D O I：

10.1016/j.cellimm.2005.04.006

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

According to the hygiene hypothesis, the increased incidence of allergic and autoimmune diseases in developed countries is explained by the decrease in infections. Several questions remain unsettled, concerning notably the nature of protective infections, the mechanisms of protection, the spectrum of diseases concerned by the hypothesis, the difference between triggering and protective infections and lastly the strategies which could be devised to mimic the effect of infections. (c) 2005 Elsevier Inc. All rights reserved.

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收藏

页码：158 / 161

页数：4

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