The genealogical tree of a chromosome

被引:25
作者
Derrida, B
Jung-Muller, B
机构
[1] Ecole Normale Super, Phys Stat Lab, F-75231 Paris 05, France
[2] Univ Paris Sud, Lab Evolut & Systemat, F-91405 Orsay, France
[3] ENGREF, F-54042 Nancy, France
关键词
steady state; spin chain; random genealogies;
D O I
10.1023/A:1004560700396
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We consider a simple neutral model to describe the genealogy of chromosomes by taking into account the effects of both recombination and coalescence. Seen as a statistical physics problem, the model looks like an inverse problem: A number of properties such as pair or three-point correlations can be computed easily, but the prediction of global properties, in particular the average number of ancestors, remains difficult. In the absence of exact solutions, these global properties can nevertheless be estimated by the usual approximations: series expansions, Monte Carlo simulations, mean-field theory. Simulations exhibit also non-self-averaging properties similar to those of mean-field spin glasses.
引用
收藏
页码:277 / 298
页数:22
相关论文
共 17 条
[1]  
Abramowitz M., 1970, HDB MATH FUNCTIONS
[2]   MITOCHONDRIAL-DNA AND HUMAN-EVOLUTION [J].
CANN, RL ;
STONEKING, M ;
WILSON, AC .
NATURE, 1987, 325 (6099) :31-36
[3]  
DERRIDA B, 1991, B MATH BIOL, V53, P355, DOI 10.1007/BF02460723
[4]   From random walks to spin glasses [J].
Derrida, B .
PHYSICA D-NONLINEAR PHENOMENA, 1997, 107 (2-4) :186-198
[5]   STATISTICAL PROPERTIES OF RANDOMLY BROKEN OBJECTS AND OF MULTIVALLEY STRUCTURES IN DISORDERED-SYSTEMS [J].
DERRIDA, B ;
FLYVBJERG, H .
JOURNAL OF PHYSICS A-MATHEMATICAL AND GENERAL, 1987, 20 (15) :5273-5288
[6]   Coalescents and genealogical structure under neutrality [J].
Donnelly, P ;
Tavare, S .
ANNUAL REVIEW OF GENETICS, 1995, 29 :401-421
[7]   Extremal properties of random systems [J].
Frachebourg, L ;
Ispolatov, I ;
Krapivsky, PL .
PHYSICAL REVIEW E, 1995, 52 (06) :R5727-R5730
[8]   FREQUENCY-DISTRIBUTIONS IN POPULATION-GENETICS PARALLEL THOSE IN STATISTICAL PHYSICS [J].
HIGGS, PG .
PHYSICAL REVIEW E, 1995, 51 (01) :95-101
[9]   PROPERTIES OF A NEUTRAL ALLELE MODEL WITH INTRAGENIC RECOMBINATION [J].
HUDSON, RR .
THEORETICAL POPULATION BIOLOGY, 1983, 23 (02) :183-201
[10]  
HUDSON RR, 1991, OXF SURV EVOL BIOL, V7, P1