Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells

被引:94
作者
Colla, S. [1 ]
Storti, P. [1 ]
Donofrio, G. [2 ]
Todoerti, K. [3 ,4 ]
Bolzoni, M. [1 ]
Lazzaretti, M. [5 ]
Abeltino, M. [1 ]
Ippolito, L. [6 ]
Neri, A. [3 ,4 ]
Ribatti, D. [7 ]
Rizzoli, V. [1 ]
Martella, E. [8 ]
Giuliani, N. [1 ]
机构
[1] Univ Parma, Dept Internal Med & Biomed Sci, Hematol & Bone Marrow Transplantat Ctr, I-43100 Parma, Italy
[2] Univ Parma, Dipartimento Salute Anim, Sez Malattie Infett, I-43100 Parma, Italy
[3] Univ Milan, Dept Med Sci, Hematol Unit 1, Milan, Italy
[4] Fdn IRCCS Policlin, Bone Marrow Transplantat Ctr, Milan, Italy
[5] Univ Parma, Dipartimento Genet, I-43100 Parma, Italy
[6] Univ Parma, Azienda Osped, Lab Diagnost Ematochim, I-43100 Parma, Italy
[7] Univ Bari, Dept Human Anat, Bari, Italy
[8] Univ Parma, Dept Pathol & Lab Med, Azienda Osped, I-43100 Parma, Italy
关键词
ANGIOGENESIS; EXPRESSION; HIF-1;
D O I
10.1038/leu.2010.193
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1967 / 1970
页数:5
相关论文
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