Incidence and prevalence of heart failure in elderly persons, 1994-2003

被引:239
作者
Curtis, Lesley H. [1 ,3 ]
Whellan, David J. [1 ,2 ,3 ,5 ]
Hammill, Bradley G. [1 ]
Hernandez, Adrian F. [1 ,2 ,3 ]
Anstrom, Kevin J. [1 ,2 ,4 ]
Shea, Alisa M. [1 ]
Schulman, Kevin A. [1 ,3 ]
机构
[1] Duke Univ, Sch Med, Duke Clin Res Inst, Ctr Clin & Genet Econ, Durham, NC 27715 USA
[2] Duke Clin Res Inst, Outcomes Res & Assessment Grp, Durham, NC 27715 USA
[3] Duke Univ, Sch Med, Dept Med, Durham, NC 27706 USA
[4] Duke Univ, Sch Med, Dept Biostat & Bioinformat, Durham, NC 27706 USA
[5] Thomas Jefferson Univ, Dept Med, Philadelphia, PA 19107 USA
关键词
D O I
10.1001/archinternmed.2007.80
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Background: Recent analyses have presented conflicting evidence regarding the incidence and prevalence of heart failure in the United States. We sought to estimate the annual incidence and prevalence of heart failure and associated survival in elderly persons from January 1, 1994, through December 31, 2003. Methods: We conducted a retrospective cohort study of 622 789 Medicare beneficiaries 65 years or older who were diagnosed as having heart failure between 1994 and 2003. The main outcome measures were incidence and prevalence of heart failure and survival following a heart failure diagnosis. Results: The incidence of heart failure declined from 32 per 1000 person-years in 1994 to 29 per 1000 person-years in 2003 (P <.01). Incidence declined most sharply among beneficiaries aged 80 to 84 years (from 57.5 to 48.4 per 1000 person-years, P <.01) and increased slightly among beneficiaries aged 65 to 69 years (from 17.5 to 19.3 per 1000 person-years, P<.01). Although risk-adjusted mortality declined slightly from 1994 to 2003, the prognosis for patients diagnosed as having heart failure remains poor. In 2002, risk-adjusted I-year mortality was 27.5%, more than 3 times higher than for age and sex-matched patients. Conclusions: Although the incidence of heart failure has declined somewhat during the past decade, modest survival gains have resulted in an increase in the number of patients living with heart failure. identifying optimal strategies for the treatment and management of heart failure will become increasingly important as the size of the Medicare population grows.
引用
收藏
页码:418 / 424
页数:7
相关论文
共 33 条
[1]
Anglotensin-converting enzyme inhibitors in coronary artery disease and preserved left ventricular systolic function - A systematic review and meta-analysis of randomized controlled trials [J].
Al-Mallah, MH ;
Tleyjeh, IM ;
Abdel-Latif, AA ;
Weaver, WD .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 47 (08) :1576-1583
[2]
[Anonymous], 2004, COCHRANE DB SYST REV, DOI DOI 10.1002/14651858.CD002901.PUB2
[3]
Effect of propranolol versus no propranolol on total mortality plus nonfatal myocardial infarction in older patients with prior myocardial infarction, congestive heart failure, and left ventricular ejection fraction >=40% treated with diuretics plus angiotensin-converting enzyme inhibitors [J].
Aronow, WS ;
Ahn, C ;
Kronzon, I .
AMERICAN JOURNAL OF CARDIOLOGY, 1997, 80 (02) :207-209
[4]
Changing incidence and survival for heart failure in a well-defined older population, 1970-1974 and 1990 1994 [J].
Barker, WH ;
Mullooly, JP ;
Getchell, W .
CIRCULATION, 2006, 113 (06) :799-805
[5]
Accuracy of ICD-9-CM codes for identifying cardiovascular and stroke risk factors [J].
Birman-Deych, E ;
Waterman, AD ;
Yan, Y ;
Nilasena, DS ;
Radford, MJ ;
Gage, BF .
MEDICAL CARE, 2005, 43 (05) :480-485
[6]
Heart failure survival among older adults in the United States - A poor prognosis for an emerging epidemic in the Medicare population [J].
Croft, JB ;
Giles, WH ;
Pollard, RA ;
Keenan, NL ;
Casper, ML ;
Anda, RF .
ARCHIVES OF INTERNAL MEDICINE, 1999, 159 (05) :505-510
[7]
*CTR MED MED SERV, CHART SER
[8]
A comparative analysis of the results from 4 trials of β-blocker therapy for heart failure:: BEST, CIBIS-II, MERIT-HF, and COPERNICUS [J].
Domanski, MJ ;
Krause-Steinrauf, H ;
Massie, BM ;
Deedwania, P ;
Follmann, D ;
Kovar, D ;
Murray, D ;
Oren, R ;
Rosenberg, Y ;
Young, J ;
Zile, M ;
Eichhorn, E .
JOURNAL OF CARDIAC FAILURE, 2003, 9 (05) :354-363
[9]
The evolving diabetes burden in the United States [J].
Engelgau, MM ;
Geiss, LS ;
Saaddine, JB ;
Boyle, JP ;
Benjamin, SM ;
Gregg, EW ;
Tierney, EF ;
Rios-Burrows, N ;
Mokdad, AH ;
Ford, ES ;
Imperatore, G ;
Narayan, KMV .
ANNALS OF INTERNAL MEDICINE, 2004, 140 (11) :945-950
[10]
Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction:: a systematic overview of data from individual patients [J].
Flather, MD ;
Yusuf, S ;
Kober, L ;
Pfeffer, M ;
Hall, A ;
Murray, G ;
Torp-Pedersen, C ;
Ball, S ;
Pogue, J ;
Moyé, L ;
Braunwald, E .
LANCET, 2000, 355 (9215) :1575-1581