Improved estimates of floating absolute risk

被引:222
作者
Plummer, M [1 ]
机构
[1] Int Agcy Res Canc, F-69372 Lyon 08, France
关键词
dose response; relative risk; misspecified models; EM algorithm;
D O I
10.1002/sim.1485
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Floating absolute risks are an alternative way of presenting relative risk estimates for polychotomous risk factors. Instead of choosing one level of the risk factor as a reference category, each level is assigned a 'floated' variance which describes the uncertainty in risk without reference to another level. In this paper, a method for estimating the floated variances is presented that improves on the previously proposed 'heuristic' method. The estimates may be calculated iteratively with a simple algorithm. A benchmark for validating the floated variance estimates is also proposed and an interpretation of floating confidence intervals is given. Copyright (C) 2004 John Wiley Sons, Ltd.
引用
收藏
页码:93 / 104
页数:12
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