Efficient proline-catalyzed Michael additions of unmodified ketones to nitro olefins

被引：623

作者：

List, B

Pojarliev, P

Martin, HJ

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 16期

关键词：

D O I：

10.1021/ol015799d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Here we describe the proline-catalyzed Michael addition of unmodified ketones to nitro olefins. This novel reaction provides gamma -nitro ketones in modest enantioselectivity yet excellent yields.

引用

页码：2423 / 2425

页数：3

共 36 条

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