Efficient proline-catalyzed Michael additions of unmodified ketones to nitro olefins

被引:623
作者
List, B
Pojarliev, P
Martin, HJ
机构
[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[2] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA
关键词
D O I
10.1021/ol015799d
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Here we describe the proline-catalyzed Michael addition of unmodified ketones to nitro olefins. This novel reaction provides gamma -nitro ketones in modest enantioselectivity yet excellent yields.
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页码:2423 / 2425
页数:3
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