Fatal Mycoplasma pneumoniae pneumonia in a previously healthy 18-year-old girl

被引:13
作者
Daxboeck, Florian
Eisl, Bernhard
Burghuber, Christofer
Memarsadeghi, Mazda
Assadian, Ojan
Stanek, Gerold
机构
[1] Univ Vienna, Div Hosp Hyg, Clin Inst Hyg & Med Microbiol, A-1090 Vienna, Austria
[2] Univ Vienna, Vienna Gen Hosp, Clin Inst Hyg & Med Microbiol, Div Hosp Hyg, A-1090 Vienna, Austria
[3] Med Univ Vienna, Vienna Gen Hosp, Dept Transplant Surg, Vienna, Austria
[4] Med Univ Vienna, Vienna Gen Hosp, Dept Radiol, Vienna, Austria
[5] Med Univ Vienna, Div Infect & Immunol, Clin Inst Hyg & Med Microbiol, Vienna, Austria
关键词
mycoplasma pneumoniae; necrotizing pneumonia; multi-organ failure;
D O I
10.1007/s00508-007-0810-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A case of fatal Mycoplasma pneumoniae pneumonia in a previously healthy 18-year-old girl is reported. On hospital day 9, the antibody titer to M. pneumoniae was 1:512 in the complement fixation test and 1:5120 in the microparticle agglutination assay. After five weeks in the intensive care unit, the patient died from necrotizing hemorrhagic pneumonia with multi-organ failure. No significant superinfections occurred during ICU treatment. Corticosteroids (hospital day 8 onward) did not influence the course of the disease. It is noteworthy that, as in some previously reported cases, the clinical state deteriorated during presumably adequate antibiotic treatment (2 days before admission onward), and despite documented eradication of the pathogen from the respiratory tract (PCR from bronchoalveolar fluid on hospital day 22 was negative). However, the illness had lasted for several days before admission to the hospital, therefore the potentially beneficial effect of antibiotic treatment at an early stage of the disease cannot be assessed. Clearly, in default of other treatment options, correct diagnosis and early treatment of mycoplasma community-acquired pneumonia seems mandatory. This is the third case of fatal mycoplasma pneumonia reported from Austria in recent years, making this topic worthy of further scientific attention.
引用
收藏
页码:379 / 384
页数:6
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