Age-Related Differences in the Frequency of Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents

被引：63

作者：

Hekkala, Anne ^{[1
]}

Reunanen, Antti ^{[2
,4
]}

Koski, Matti ^{[3
]}

Knip, Mikael ^{[3
,4
,5
]}

Veijola, Riitta ^{[1
]}

机构：

[1] Univ Oulu, Dept Pediat, Oulu Univ Hosp, SF-90100 Oulu, Finland

[2] Natl Publ Hlth Inst, Helsinki, Finland

[3] Univ Helsinki, Hosp Children & Adolescents, Helsinki, Finland

[4] Folkhalsan Res Ctr, Helsinki, Finland

[5] Tampere Univ Hosp, Dept Pediat, Tampere, Finland

来源：

DIABETES CARE | 2010年 / 33卷 / 07期

关键词：

ONSET;

D O I：

10.2337/dc09-2344

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE - We studied the prevalence of diabetic ketoacidosis (DKA) at diagnosis of type 1 diabetes in children in Finland. RESEARCH DESIGN AND METHODS - From 2002 to 2005, data on virtually all children <15 years of age diagnosed with type 1 diabetes (n = 1,656) in Finland were collected. RESULTS - DKA was present in 19.4% of the case subjects, and 4.3% had severe DKA. In children aged 0-4, 5-9, and 10-14 years, DKA was present in 16.5, 14.8, and 26.4%, respectively (P < 0.001). Severe DKA occurred in 3.7, 3.1, and 5.9%, respectively (P = 0.048). DKA was present in 30.1% and severe DKA in 7.8% of children aged <2 years. CONCLUSION - The overall frequency of DKA in children is low in Finland at diagnosis of type 1 diabetes. However, both children <2 years of age and adolescents aged 10-14 years are at increased risk of DKA.

引用

页码：1500 / 1502

页数：3

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