The Meaning of Interaction

被引：88

作者：

Wang, Xuefeng ^{[1
]}

Elston, Robert C. ^{[1
]}

Zhu, Xiaofeng ^{[1
]}

机构：

[1] Case Western Reserve Univ, Dept Epidemiol & Biostat, Cleveland, OH 44106 USA

来源：

HUMAN HEREDITY | 2010年 / 70卷 / 04期

关键词：

Epistasis; Gametic phase disequilibriurn; Interaction; Transformation; GENOME-WIDE ASSOCIATION; STATISTICAL-METHODS; GENE INTERACTIONS; EPISTASIS; VARIANCE; ADDITIVITY; LOCI;

D O I：

10.1159/000321967

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Although recent studies have attempted to dispel the confusion that exists in regard to the definition, analysis and interpretation of interaction in genetics, there still remain aspects that are poorly understood by non-statisticians. After a brief discussion of the definition of gene-gene interaction, the main part of this study addresses the fundamental meaning of statistical interaction and its relationship to measurement scale, disproportionate sample sizes in the cells of a two-way table and gametic phase disequilibrium. Copyright (C) 2010 S. Karger AG, Basel

引用

页码：269 / 277

页数：9

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