Unusual Isomeric Corniculatolides from Mangrove, Aegiceras corniculatum

被引：27

作者：

Ponnapalli, M. Gowri ^{[1
]}

Annam, S. Ch. V. A. Rao

Ravirala, Saidulu

Sukki, Sushma

Ankireddy, Madhu

Tuniki, V. Raju ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Ctr NMR & Struct Chem, Hyderabad 500607, Andhra Pradesh, India

来源：

JOURNAL OF NATURAL PRODUCTS | 2012年 / 75卷 / 02期

关键词：

ANTINEOPLASTIC AGENTS; MACROCYCLIC LACTONE;

D O I：

10.1021/np200789s

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new isomeric macrolides of combretastatin D-2 congeners named isocorniculatolide A (1), 11-O-methylisocorniculatolide A (2), 11-O-methylcomiculatolide A (3), and 12-hydroxy-11-O-methylcorniculatolide A (4), and the known corniculatolide A (5), arjunolic acid, and maslinic acid were isolated from the CHCl3 extract of the bark of Aegiceras corniculatum. The structures of the new compounds (1-4) were elucidated by a combination of spectroscopic analysis (1-5), chemical modifications, and single-crystal X-ray analysis (1).

引用

页码：275 / 279

页数：5

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