Visual contrast processing in migraine

被引:78
作者
Shepherd, AJ [1 ]
机构
[1] Univ London Birkbeck Coll, Sch Psychol, London WC1E 7HX, England
关键词
migraine; vision; pattern sensitivity; contrast; spatial frequency;
D O I
10.1046/j.1468-2982.2000.00119.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Some migraine sufferers report certain visual patterns can reliably trigger a migraine attack, such as high contrast striped patterns or flickering lights. Differences between people with and without migraine on tasks that involve these patterns have been attributed to abnormal cortical processing in migraine, although the locus and extent of the abnormality remains unclear, as is any relationship between impairment on various visual tasks. In this study 58 migraine sufferers and 61 control subjects participated in three visual tasks involving striped patterns. One assessed pattern sensitivity with high contrast patterns, the second detection thresholds for low contrast patterns and the third supra-threshold contrast scaling. With each measure, the performance of migraine sufferers as a group differed to the performance of non-migraine control subjects. There were no significant differences between the migraine subgroups when classified according to the presence or absence of aura. Cross-correlating the results from the three tasks, however, revealed consistent associations: impaired or extreme responses on one task were associated with impaired or extreme responses on the others. There were no overall effects due to migraine duration, the frequency of migraine attacks or the time since the last attack. These results are discussed in the context of visually induced migraine, proposed causes of abnormal cortical function in migraine and the prospects for developing clinically useful tests of visual function.
引用
收藏
页码:865 / 880
页数:16
相关论文
共 45 条
[1]   Visual evoked potentials during long periods of pattern-reversal stimulation in migraine [J].
Afra, J ;
Cecchini, AP ;
De Pasqua, V ;
Albert, A ;
Schoenen, J .
BRAIN, 1998, 121 :233-241
[2]  
[Anonymous], MIGRAINE PHARM GENET
[3]   Functional MRI-BOLD of visually triggered headache in patients with migraine [J].
Cao, Y ;
Welch, KMA ;
Aurora, S ;
Vikingstad, EM .
ARCHIVES OF NEUROLOGY, 1999, 56 (05) :548-554
[4]   MIGHT MIGRAINE DAMAGE THE BRAIN [J].
CHRONICLE, E ;
MULLENERS, W .
CEPHALALGIA, 1994, 14 (06) :415-418
[5]   THRESHOLDS FOR DETECTION OF A TARGET AGAINST A BACKGROUND GRATING SUGGEST VISUAL DYSFUNCTION IN MIGRAINE WITH AURA BUT NOT MIGRAINE WITHOUT AURA [J].
CHRONICLE, EP ;
WILKINS, AJ ;
COLESTON, DM .
CEPHALALGIA, 1995, 15 (02) :117-122
[6]   Visual system dysfunction in migraine: A review of clinical and psychophysical findings [J].
Chronicle, EP ;
Mulleners, WM .
CEPHALALGIA, 1996, 16 (08) :525-535
[7]  
Coleston D. M., 1993, CEPHALALGIA S13, V13, P11
[8]   RESPONSES TO TEMPORAL VISUAL-STIMULI IN MIGRAINE - THE CRITICAL FLICKER FUSION TEST [J].
COLESTON, DM ;
KENNARD, C .
CEPHALALGIA, 1995, 15 (05) :396-398
[9]   PRECORTICAL DYSFUNCTION OF SPATIAL AND TEMPORAL VISUAL PROCESSING IN MIGRAINE [J].
COLESTON, DM ;
CHRONICLE, E ;
RUDDOCK, KH ;
KENNARD, C .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1994, 57 (10) :1208-1211
[10]   Perfusion-weighted imaging defects during spontaneous migrainous aura [J].
Cutrer, FM ;
Sorensen, AG ;
Weisskoff, RM ;
Ostergaard, L ;
del Rio, MS ;
Lee, EJ ;
Rosen, BR ;
Moskowitz, MA .
ANNALS OF NEUROLOGY, 1998, 43 (01) :25-31