We report the 0.5-10 keV X-ray image and spectrum of Cl 0016 + 16, which, at a redshift of 0.541, is one of the most distant clusters of galaxies observed with ASCA. The ASCA X-ray image is well represented by an isothermal beta model. The best-fit parameters for the core radius (theta(c)) and beta are 0.'6 and 0.7, respectively. However, because of ASCA's moderate spatial resolution, these two parameters are strongly correlated. The observed spectrum within a 6' radius is well fitted by a thin thermal emission model with a plasma temperature of 8.0 +/- 1.0 keV. The Sunyaev-Zeldovich (SZ) effect in Cl 0016+16 has been observed by Carlstrom et al. using an interferometer and by Birkinshaw et al. using a single-dish radio telescope. Combining the SZ microwave decrement with the plasma density and temperature profiles derived from our X-ray observation, we obtained a value of the Hubble constant of 47 +/- 14 km s(-1) Mpc(-1) with the profile parameters obtained by interferometric data, and 52 +/- 20 km s(-1) Mpc(-1) with our best-fit shape parameters and single-dish telescope data.