Do cells need CDK2 and ... Bcr-Abl?

被引:21
作者
Blagosklonny, MV [1 ]
机构
[1] New York Med Coll, Brander Canc Res Inst, Valhalla, NY 10595 USA
关键词
D O I
10.1038/sj.cdd.4401361
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:249 / 251
页数:3
相关论文
共 47 条
[1]   SIGNALING BY ABL ONCOGENES THROUGH CYCLIN D1 [J].
AFAR, DEH ;
MCLAUGHLIN, J ;
SHERR, CJ ;
WITTE, ON ;
ROUSSEL, MF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (21) :9540-9544
[2]  
Aleem E, 2004, CELL CYCLE, V3, P35
[3]   Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome c and activation of caspase-3 [J].
Amarante-Mendes, GP ;
Kim, CN ;
Liu, L ;
Huang, Y ;
Perkins, CL ;
Green, DR ;
Bhalla, K .
BLOOD, 1998, 91 (05) :1700-1705
[4]   Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis:: protection is correlated with up regulation of Bcl-xL [J].
Amarante-Mendes, GP ;
McGahon, AJ ;
Nishioka, WK ;
Afar, DEH ;
Witte, ON ;
Green, DR .
ONCOGENE, 1998, 16 (11) :1383-1390
[5]   Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death [J].
Amarante-Mendes, GP ;
Finucane, DM ;
Martin, SJ ;
Cotter, TG ;
Salvesen, GS ;
Green, DR .
CELL DEATH AND DIFFERENTIATION, 1998, 5 (04) :298-306
[6]   Cdk2 knockout mice are viable [J].
Berthet, C ;
Aleem, E ;
Coppola, V ;
Tessarollo, L ;
Kaldis, P .
CURRENT BIOLOGY, 2003, 13 (20) :1775-1785
[7]   Cyclotherapy Protection of Normal Cells and Unshielding of Cancer Cells [J].
Blagosklonny, Mikhail V. ;
Darzynkiewicz, Zbigniew .
CELL CYCLE, 2002, 1 (06) :375-382
[8]   The Restriction Point of the Cell Cycle [J].
Blagosklonny, Mikhail V. ;
Pardee, Arthur B. .
CELL CYCLE, 2002, 1 (02) :103-110
[9]   Cell senescence and hypermitogenic arrest [J].
Blagosklonny, MV .
EMBO REPORTS, 2003, 4 (04) :358-362
[10]   The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy [J].
Blagosklonny, MV ;
Fojo, T ;
Bhalla, KN ;
Kim, JS ;
Trepel, JB ;
Figg, WD ;
Rivera, Y ;
Neckers, LM .
LEUKEMIA, 2001, 15 (10) :1537-1543