Escherichia coli outer membrane protein TolC is involved in production of the peptide antibiotic microcin J25

被引：47

作者：

Delgado, MA

Solbiati, JO

Chiuchiolo, MJ

Farías, RN

Salomón, RA ^{[1
]}

机构：

[1] Univ Nacl Tucuman, Consejo Nacl Invest Cient & Tecn, Inst Super Invest Biol, Dept Bioquim Nutr, RA-4000 San Miguel De Tucuman, Tucuman, Argentina

[2] Univ Nacl Tucuman, Inst Quim Biol Dr Bernabe Bloj, RA-4000 San Miguel De Tucuman, Tucuman, Argentina

来源：

JOURNAL OF BACTERIOLOGY | 1999年 / 181卷 / 06期

关键词：

D O I：

10.1128/JB.181.6.1968-1970.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A Tn5 insertion in tolC eliminated microcin J25 production. The mutation had little effect on the expression of the microcin structural gene and presumably acted by blocking microcin secretion. The tolC mutants carrying multiple copies of the microcin genes were less immune to the microcin. TolC is thus likely a component of a microcin export complex containing the McjD immunity protein, an ABC exporter.

引用

页码：1968 / 1970

页数：3

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