The neurotransmitter g-aminobutyric acid has long been thought to have an inhibitory effect on neurotransmission. But a new study shows that, in cells of the suprachiasmatic nucleus (SCN), GABA can be excitatory. Moreover, cells of the SCN are responsible for the generation of circadian rhythms in mammals, and GABA seems to act as an excitatory neurotransmitter only during the day.
机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
TUREK, FW
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PINTO, LH
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机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
PINTO, LH
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VITATERNA, MH
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机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
VITATERNA, MH
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PENEV, PD
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机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
PENEV, PD
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ZEE, PC
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机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
ZEE, PC
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TAKAHASHI, JS
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机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
TUREK, FW
;
PINTO, LH
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机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
PINTO, LH
;
VITATERNA, MH
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机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
VITATERNA, MH
;
PENEV, PD
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机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
PENEV, PD
;
ZEE, PC
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机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520
ZEE, PC
;
TAKAHASHI, JS
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h-index: 0
机构:Department of Neurobiology and Physiology, NSF Science and Technology Center for Biological Timing, Northwestern University, Evanston, IL 60208-3520