Rarity of surgical complications after postchemotherapy nephrectomy for nephroblastoma. Experience of the International Society of Paediatric Oncology trial and study "SIOP-9"

被引：57

作者：

Godzinski, J

Tournade, MF

deKraker, J

Lemerle, J

Voute, PA

Weirich, A

Ludwig, R

Rapala, M

Skotnicka, G

Gauthier, F

Moorman-Voestermans, CGM

Buerger, D

VanVeen, A

Sawicz-Birkowska, K

机构：

[1] Marciniak Hosp, Dept Paediat Surg, PL-50420 Wroclaw, Poland

[2] Inst Gustave Roussy, Dept Pediat, Villejuif, France

[3] Univ Amsterdam, Acad Med Ctr, Emma Kinderziekenhuis, Dept Paediat Oncol, NL-1105 AZ Amsterdam, Netherlands

[4] Univ Heidelberg, Kinderklin, Stn Onkol Hamatol, Heidelberg, Germany

[5] Med Acad, Dept Paediat Surg, Lodz, Poland

[6] CHU Bicetre, Serv Chirurg Pediat, Le Kremlin Bicetre, France

[7] Univ Amsterdam, Acad Med Ctr, Emma Kinderziekenhuis, Dept Pediat Surg, NL-1105 AZ Amsterdam, Netherlands

[8] Med Hsch Hannover, Kinderklin, Hannover, Germany

[9] Med Acad, Dept Paediat Surg, Wroclaw, Poland

来源：

EUROPEAN JOURNAL OF PEDIATRIC SURGERY | 1998年 / 8卷 / 02期

关键词：

nephroblastoma; surgical complications; preoperative chemotherapy;

D O I：

10.1055/s-2008-1071127

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The aim of the study was to assess rates and types of nephrectomy-related complications in children nephrectomized for nephroblastoma after preoperative chemotherapy. Records of 598 Wilms' tumour patients registered in the International Society of Paediatric Oncology Trial & Study No. 9 (SIOP-9), and pretreated correctly according to the protocol with vincristine + actinomycin D +/- epirubicine or adriamycin prior to nephrectomy, were retrospectively reviewed. Forty-nine patients (8 %), who suffered from 54 complications, were identified. Most frequent events were small-bowel occlusions (3.7 %) and tumour ruptures (2.8 %). Other complications were registered in 2.0 % of cases. The low rate of nephrectomy complications and no deaths related to registered ones, are another argument for preoperative chemotherapy in Wilms' tumour patients.

引用

页码：83 / 86

页数：4

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