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TRP channels as cellular sensors

被引：2087
作者：
Clapham, DE [1 ]
机构：
[1] Harvard Univ, Childrens Hosp Boston, Sch Med,Dept Neurobiol, Howard Hughes Med Inst, Boston, MA 02115 USA
来源：
NATURE | 2003年 / 426卷 / 6966期
关键词：
D O I：
10.1038/nature02196
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
TRP channels are the vanguard of our sensory systems, responding to temperature, touch, pain, osmolarity, pheromones, taste and other stimuli. But their role Is much broader than classical sensory transduction. They are an ancient sensory apparatus for the cell, not just the multicellular organism, and they have been adapted to respond to all manner of stimuli, from both within and outside the cell.
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页码：517 / 524
页数：8
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