A synthesis of functionalized indoline 2,2-biscarboxylates

被引：2

作者：

Wright, SW

Dow, RL

McClure, LD

Hageman, DL

机构：

[1] Pfizer Central Research, Groton, CT 06340, Eastern Point Road

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 39期

关键词：

D O I：

10.1016/0040-4039(96)01573-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthetic approach to a structurally novel series of indoline 2,2-biscarboxylates is employs a tandem bis-alkylation strategy to cyclize the indoline heteroring from the bromide 7 and diethyl bromomalonate. The indolines thus prepared may be N-deprotected and further functionalized on the indoline nitrogen. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6965 / 6968

页数：4

共 12 条

[1] 2,2-DISUBSTITUTED-1,2-DIHYDRO-3H-INDOL-3-ONES BY BASE-INDUCED AND THERMAL-INDUCED CYCLIZATIONS OF ORTHO-AZIDOPHENYL S-ALKYL KETONES AND O-AZIDOBENZOYL ESTERS [J].