Leukemogenesis by Moloney murine leukemia virus: A multistep process

被引：102

作者：

Fan, H ^{[1
]}

机构：

[1] UNIV CALIF IRVINE,CANC RES INST,IRVINE,CA 92717

来源：

TRENDS IN MICROBIOLOGY | 1997年 / 5卷 / 02期

关键词：

D O I：

10.1016/S0966-842X(96)10076-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Moloney murine leukemia virus is a prototypical simple retrovirus that has been an extremely useful model for leukemogenesis. Important steps in leukemogenesis include proviral activation of cellular proto-oncogenes, generation of mink cell focus-inducing recombinants, and early (preleukemic) virus-induced changes in hematopoiesis.

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页码：74 / 82

页数：9

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