Diagnostic approach to platelet function disorders

被引：23

作者：

Hayward, Catherine P. M. ^{[1
,2
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机构：

[1] McMaster Univ, Med Ctr, Dept Pathol & Mol Med, Hamilton, ON L8N 3Z5, Canada

[2] McMaster Univ, Dept Med, Hamilton, ON L8N 3Z5, Canada

[3] Hamilton Reg Lab, Program Med, Hamilton, ON, Canada

来源：

TRANSFUSION AND APHERESIS SCIENCE | 2008年 / 38卷 / 01期

关键词：

D O I：

10.1016/j.transci.2007.12.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Platelet disorders are common bleeding disorders, with a variety of congenital and acquired causes. The diagnostic evaluation of platelet disorders challenges both clinicians and clinical laboratories, as testing for these conditions is complex, not well standardized and time consuming. An understanding of normal platelet function has provided insights on the pathogenesis of many platelet function disorders. Knowledge of the key features of platelet disorders aids their diagnostic assessment. Tests for aggregation, secretion and dense granule defects continue to be the most helpful for the evaluation of suspected platelet function disorders. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：65 / 76

页数：12

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