Antioxidant properties of green and black tea, and their potential ability to retard the progression of eye lens cataract

被引:51
作者
Thiagarajan, G
Chandani, S
Sundari, CS
Rao, SH
Kulkarni, AV
Balasubramanian, D
机构
[1] Hyderabad Eye Res Fdn, LV Prasad Eye Inst, Hyderabad 500034, Andhra Pradesh, India
[2] Ctr Cellular & Mol Biol, Hyderabad 500007, Andhra Pradesh, India
关键词
tea extracts; antioxidants; comet assays; eye lens proteins; selenite cataract;
D O I
10.1006/exer.2001.1049
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Aqueous extracts of green and black tea are shown to quench reactive oxygen species such as singlet oxygen, superoxide and hydroxyl radicals, prevent the oxidative cross-linking of test proteins and inhibit single strand breakage of DNA in whole cells, They are also seen to be able to counteract the oxidative insult mounted by cigarette smoke. In rats in which cataract was induced by subcutaneous injection of selenite, administration of green or black tea extracts led to a retardation of the progression of lens opacity, suggesting the potential cataracto-static ability of tea. (C) 2001 Academic Press.
引用
收藏
页码:393 / 401
页数:9
相关论文
共 44 条
[1]  
BALASUBRAMANIAN D, 1998, EXP EYE RES, V67, pS212
[2]  
BHUYAN KC, 1981, IRCS MED SCI-BIOCHEM, V9, P194
[3]  
BHUYAN KC, 1981, IRCS MED SCI-BIOCHEM, V9, P195
[4]  
CHAKRABARTI B, 1986, J INDIAN CHEM SOC, V63, P131
[5]  
Deng ZY, 1998, J AGR FOOD CHEM, V46, P3875, DOI 10.1021/jf980105+
[6]   PREVENTION OF SELENITE CATARACT BY VITAMIN-C [J].
DEVAMANOHARAN, PS ;
HENEIN, M ;
MORRIS, S ;
RAMACHANDRAN, S ;
RICHARDS, RD ;
VARMA, SD .
EXPERIMENTAL EYE RESEARCH, 1991, 52 (05) :563-568
[7]  
GRUNBERGER D, 1997, Patent No. 5591773
[8]   PREVENTIVE EFFECTS OF GREEN TEA AGAINST LIVER OXIDATIVE DNA-DAMAGE AND HEPATOTOXICITY IN RATS TREATED WITH 2-NITROPROPANE [J].
HASEGAWA, R ;
CHUJO, T ;
SAIKATO, K ;
UMEMURA, T ;
TANIMURA, A ;
KUROKAWA, Y .
FOOD AND CHEMICAL TOXICOLOGY, 1995, 33 (11) :961-&
[9]   Natural polyphenols (vegetable tannins) as drugs: Possible modes of action [J].
Haslam, E .
JOURNAL OF NATURAL PRODUCTS, 1996, 59 (02) :205-215
[10]   CONTENT OF POTENTIALLY ANTICARCINOGENIC FLAVONOIDS OF TEA INFUSIONS, WINES, AND FRUIT JUICES [J].
HERTOG, MGL ;
HOLLMAN, PCH ;
VANDEPUTTE, B .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1993, 41 (08) :1242-1246