The role of caveolae and caveolin in vesicle-dependent and vesicle-independent trafficking

被引：82

作者：

Matveev, S ^{[1
]}

Li, XG ^{[1
]}

Everson, W ^{[1
]}

Smart, EJ ^{[1
]}

机构：

[1] Univ Kentucky, Sch Med, Dept Physiol, Lexington, KY 40536 USA

来源：

ADVANCED DRUG DELIVERY REVIEWS | 2001年 / 49卷 / 03期

关键词：

potocytosis; cholera toxin; endocytosis; transcytosis; cholesterol; trafficking;

D O I：

10.1016/S0169-409X(01)00138-7

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Caveolae can mediate endocytosis, transcytosis, and potocytosis. Our understanding of these processes as well as the elucidation of the molecular machinery involved has greatly expanded. In addition, caveolin, a 22 kDa protein often associated with caveolae, can promote the trafficking of sterol through the cytoplasm independent of vesicles. Caveolin also influences the formation, morphology, and function of caveolae. The ability of caveolae and caveolin to mediate macromolecular transport directly impacts a variety of physiological and pathophysiological processes. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：237 / 250

页数：14

共 82 条

[1] POTOCYTOSIS - SEQUESTRATION AND TRANSPORT OF SMALL MOLECULES BY CAVEOLAE [J].

ANDERSON, RGW ;

KAMEN, BA ;

ROTHBERG, KG ;

LACEY, SW .

SCIENCE, 1992, 255 (5043) :410-411

[2] CAVEOLAE - WHERE INCOMING AND OUTGOING MESSENGERS MEET [J].

ANDERSON, RGW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (23) :10909-10913

[3] The caveolae membrane system [J].

Anderson, RGW .

ANNUAL REVIEW OF BIOCHEMISTRY, 1998, 67 :199-225

[4] Murine SR-BI, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolae [J].

Babitt, J ;

Trigatti, B ;

Rigotti, A ;

Smart, EJ ;

Anderson, RGW ;

Xu, SZ ;

Krieger, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (20) :13242-13249

[5]

Bilderback TR, 1997, J BIOL CHEM, V272, P10922

[6] Oxidized low density lipoprotein displaces endothelial nitric-oxide synthase (eNOS) from plasmalemmal caveolae and impairs eNOS activation [J].

Blair, A ;

Shaul, PW ;

Yuhanna, IS ;

Conrad, PA ;

Smart, EJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (45) :32512-32519

[7] SORTING OF GPI-ANCHORED PROTEINS TO GLYCOLIPID-ENRICHED MEMBRANE SUBDOMAINS DURING TRANSPORT TO THE APICAL CELL-SURFACE [J].

BROWN, DA ;

ROSE, JK .

CELL, 1992, 68 (03) :533-544

[8] LOWERING THE CHOLESTEROL CONTENT OF MA104 CELLS INHIBITS RECEPTOR-MEDIATED TRANSPORT OF FOLATE [J].

CHANG, WJ ;

ROTHBERG, KG ;

KAMEN, BA ;

ANDERSON, RGW .

JOURNAL OF CELL BIOLOGY, 1992, 118 (01) :63-69

[9] PURIFICATION AND CHARACTERIZATION OF SMOOTH-MUSCLE CELL CAVEOLAE [J].

CHANG, WJ ;

YING, YS ;

ROTHBERG, KG ;

HOOPER, NM ;

TURNER, AJ ;

GAMBLIEL, HA ;

DEGUNZBURG, J ;

MUMBY, SM ;

GILMAN, AG ;

ANDERSON, RGW .

JOURNAL OF CELL BIOLOGY, 1994, 126 (01) :127-138

[10] SIGNAL-TRANSDUCTION OF A G-PROTEIN-COUPLED RECEPTOR IN CAVEOLAE - COLOCALIZATION OF ENDOTHELIN AND ITS RECEPTOR WITH CAVEOLIN [J].

CHUN, MY ;

LIYANAGE, UK ;

LISANTI, MP ;

LODISH, HF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (24) :11728-11732

← 1 2 3 4 5 6 7 8 9 →