Direct transcriptional control of the Arabidopsis immune receptor FLS2 by the ethylene-dependent transcription factors EIN3 and EIL1

被引:176
作者
Boutrot, Freddy [1 ]
Segonzac, Cecile [1 ]
Chang, Katherine N. [2 ]
Qiao, Hong [2 ]
Ecker, Joseph R. [2 ]
Zipfel, Cyril [1 ]
Rathjen, John P. [1 ]
机构
[1] Sainsbury Lab, Norwich NR4 7UH, Norfolk, England
[2] Salk Inst Biol Studies, Plant Biol Lab, La Jolla, CA 92093 USA
基金
美国国家科学基金会; 英国生物技术与生命科学研究理事会;
关键词
innate immunity; receptor kinase; PLANT INNATE IMMUNITY; F-BOX PROTEINS; PSEUDOMONAS-SYRINGAE; BACTERIAL FLAGELLIN; DISEASE RESISTANCE; THALIANA; KINASE; PERCEPTION; RESPONSES; ETHYLENE-INSENSITIVE3;
D O I
10.1073/pnas.1003347107
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
In plant innate immunity, the leucine-rich repeat receptor kinase FLS2 recognizes the bacterial pathogen-associated molecular pattern (PAMP) flagellin. The molecular mechanisms underlying PAMP perception are not fully understood. Here, we reveal that the gaseous phytohormone ethylene is an integral part of PAMP-triggered immunity. Plants mutated in the key ethylene-signaling protein EIN2 are impaired in all FLS2-mediated responses, correlating with reduced FLS2 transcription and protein accumulation. The EIN3 and EIN3-like transcription factors, which depend on EIN2 activity for their accumulation, directly control FLS2 expression. Our results reveal a direct role for ethylene in regulation of an innate immune receptor.
引用
收藏
页码:14502 / 14507
页数:6
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