Infrequent reinfection after successful treatment for hepatitis C virus infection in injection drug users

被引：86

作者：

Backmund, M

Meyer, K

Edlin, BR

机构：

[1] Cornell Univ, Ctr Study Hepatitis C, Weill Med Coll, New York, NY 10021 USA

[2] Gen Hosp Munich Schwabing, Dept Addict Med, Munich, Germany

来源：

CLINICAL INFECTIOUS DISEASES | 2004年 / 39卷 / 10期

关键词：

D O I：

10.1086/425361

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We followed-up 18 injection drug users for a mean of 33.8 months (range, 4-55 months) after successful treatment for hepatitis C virus (HCV) infection. Fifteen (83%) of the patients remained HCV RNA-negative, 1 patient was not tested, and 2 patients had test results positive for HCV RNA. The estimated rate of reinfection as a result of injection drug use was 0-4.1 cases per 100 person-years (cumulative incidence, 0%-12.6% at 48 months after completion of treatment). Of 50 patients originally treated, 15 (30%) were HCV RNA-negative 3 years later.

引用

收藏

页码：1540 / 1543

页数：4

相关论文

共 37 条

[1] The importance of preventing hepatitis C virus infection among injection drug users in the United States [J].

Alter, MJ ;

Moyer, LA .

JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1998, 18 :S6-S10

[2] National Institutes of Health Consensus Development Conference Statement: Management of hepatitis C: 2002 - June 10-12, 2002 [J].

不详 .

HEPATOLOGY, 2002, 36 (05) :S3-S20

[3]

[Anonymous], 1999, J Hepatol, V30, P956

[4] Second infection with a different hepatitis C virus genotype in a intravenous drug user during interferon therapy [J].

Asselah, T ;

Vidaud, D ;

Doloy, A ;

Boyer, N ;

Martinot, M ;

Vidaud, M ;

Valla, D ;

Marcellin, P .

GUT, 2003, 52 (06) :900-902

[5] Hepatitis C virus infection in injection drug users in Bavaria: Risk factors for seropositivity [J].

Markus Backmund ;

Kirsten Meyer ;

Martin Wächtler ;

Dieter Eichenlaub .

European Journal of Epidemiology, 2003, 18 (6) :563-568

[6] Treatment of hepatitis C infection in injection drug users [J].

Backmund, M ;

Meyer, K ;

Von Zielonka, M ;

Eichenlaub, D .

HEPATOLOGY, 2001, 34 (01) :188-193

[7]

BACKMUND M, 2002, SUCHTTHERAPIE, V3, pS67

[8]

BACKMUND M, 2001, SUCHTMED, V3, P21

[9] Long-term course of interferon-treated chronic hepatitis C [J].

Cammà, C ;

Di Marco, V ;

Lo Iacono, O ;

Almasio, P ;

Giunta, M ;

Fuschi, P ;

Vaccaro, A ;

Fabiano, C ;

Magrin, S ;

Di Stefano, R ;

Bonura, C ;

Pagliaro, L ;

Craxì, A .

JOURNAL OF HEPATOLOGY, 1998, 28 (04) :531-537

[10] Methadone maintenance and hepatitis C virus infection among injecting drug users [J].

Crofts, N ;

Nigro, L ;

Oman, K ;

Stevenson, E ;

Sherman, J .

ADDICTION, 1997, 92 (08) :999-1005

← 1 2 3 4 →