Interaction of uropathogenic Escherichia coli with host uroepithelium

被引：46

作者：

Kau, AL ^{[1
]}

Hunstad, DA ^{[1
]}

Hultgren, SJ ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2005年 / 8卷 / 01期

关键词：

D O I：

10.1016/j.mib.2004.12.001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Investigation into the pathogenesis of Escherichia coli urinary tract infection has provided numerous insights into the mechanisms by which bacteria adhere, grow and persist in association with host tissue. Many molecular details concerning the interaction of these bacteria with their host have been elucidated, and the murine model of cystitis has generated a new paradigm by which acute and recurrent urinary tract infections may proceed. These advances could potentially result in the development of novel vaccines and therapies for this very costly disease.

引用

页码：54 / 59

页数：6

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