Porphyrin-based, light-activated antimicrobial materials

被引:85
作者
Bozja, J
Sherrill, J
Michielsen, S [1 ]
Stojiljkovic, I
机构
[1] Georgia Inst Technol, Sch Text & Fiber Engn, Atlanta, GA 30332 USA
[2] Emory Univ, Dept Microbiol, Atlanta, GA 30322 USA
[3] Georgia Inst Technol, Sch Mat Sci & Engn, Atlanta, GA 30332 USA
关键词
antimicrobial; porphyrin; nylon; surface modification; surfaces; modification; monolayers; nanolayers; polyamides;
D O I
10.1002/pola.10773
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
New light-activated antimicrobial materials with a potentially wide range of possible uses in civilian settings were synthesized by the grafting of protoporphyrin IX and zinc protoporphyrin IX to nylon fibers. These fibers were shown to be active against Staphylococcus aureus at light exposures of 10,000 lux and greater and against Escherichia coli at 60,000 lux. They were ineffective against both strains in the absence of light. At 40,000 lux, these fibers showed increased antimicrobial activity against S. aureus with increasing exposure time. (C) 2003 Wiley Periodicals, Inc.
引用
收藏
页码:2297 / 2303
页数:7
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