Acute liver failure

被引：132

作者：

O'Grady, JG ^{[1
]}

机构：

[1] Kings Coll Hosp London, Inst Liver Studies, London SE5 9PJ, England

来源：

POSTGRADUATE MEDICAL JOURNAL | 2005年 / 81卷 / 953期

关键词：

D O I：

10.1136/pgmj.2004.026005

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Acute liver failure is a complex multisystemic illness that evolves quickly after a catastrophic insult to the liver leading to the development of encephalopathy. The underlying aetiology and the pace of progression strongly influence the clinical course. The commonest causes are paracetamol, idiosyncratic drug reactions, hepatitis B, and seronegative hepatitis. The optimal care is multidisciplinary and up to half of the cases receive liver transplants, with survival rates around 75%-90%. Artificial liver support devices remain unproven in efficacy in acute liver failure.

引用

页码：148 / 154

页数：7

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