Thymic involution with ageing: Obsolescence or good housekeeping?

被引：277

作者：

George, AJT

Ritter, MA

机构：

来源：

IMMUNOLOGY TODAY | 1996年 / 17卷 / 06期

关键词：

D O I：

10.1016/0167-5699(96)80543-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The thymus undergoes premature ageing in comparison with other organs of the immune system, with involution starting soon after birth and continuing throughout life. Does this reflect a failure of repair or is the process of adaptive value? Here, Andrew George and Mary Ritter apply a cost-benefit analysis, and conclude that the scaling down of this organ has been evolutionarily advantageous to our ancestors.

引用

页码：267 / 272

页数：6

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