Mice as models of human developmental disorders: Natural and artificial mutants

被引：9

作者：

Darling, S

机构：

[1] Dept. of Anat. and Devmtl. Biology, University College London, London WC1E 6BT, Gower Street

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1996年 / 6卷 / 03期

关键词：

D O I：

10.1016/S0959-437X(96)80004-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Over the past year, the mouse has been used as a model to make significant contributions towards our understanding of human developmental disorders. The existence of both natural and artificial mouse mutants has not only facilitated the identification of mutations and provided candidate genes for human disorders but has also increased our knowledge regarding the cellular and molecular processes involved in normal mammalian embryogenesis.

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页码：289 / 294

页数：6

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