Microfabrication and array technologies for DNA sequencing and diagnostics

被引：31

作者：

ODonnellMaloney, MJ ^{[1
]}

Little, DP ^{[1
]}

机构：

[1] SEQUENOM INC,SAN DIEGO,CA 92121

来源：

GENETIC ANALYSIS-BIOMOLECULAR ENGINEERING | 1996年 / 13卷 / 06期

基金：

美国国家卫生研究院;

关键词：

microscale; immobilized oligonucleotides; miniaturization; diagnostics;

D O I：

10.1016/S1050-3862(96)00166-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

It is now possible to miniaturize numerous 'macroscale' processes and develop microfabricated devices to replace conventional equipment. Such advances have lead to the development of arrays of immobilized oligonuceotides useful for basic research, diagnostic studies, sequence analysis and a number of novel applications. Additionally, standard laboratory equipment has been redesigned on a microscale level to increase efficiency many processes have been integrated onto one chip since miniaturization call be readily achieved. (C) 1996 Elsevier Science B.V.

引用

页码：151 / 157

页数：7