Optimisation of extraction procedure for black fungus polysaccharides and effect of the polysaccharides on blood lipid and myocardium antioxidant enzymes activities

被引：96

作者：

Ma Jiangwei ^{[1
]}

Qiao Zengyong ^{[1
]}

Xiang Xia ^{[1
]}

机构：

[1] Shanghai 6th Peoples Hosp, Fengxian Branch, Dept Cardiovasc Med, Shanghai 201400, Peoples R China

来源：

CARBOHYDRATE POLYMERS | 2011年 / 84卷 / 03期

关键词：

Black fungus polysaccharides; Antitumour activities; Blood lipid; High fat diet; Cardiovascular diseases; CORONARY-HEART-DISEASE; RISK; GLUTATHIONE; HYPERLIPIDEMIA; FLAVONOIDS; MANAGEMENT; LENTINAN; TISSUE;

D O I：

10.1016/j.carbpol.2010.12.068

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Optimal conditions for the extraction of black fungus polysaccharides were 350 W, 5, 35 min and 90 degrees C, for ultrasonic power, ratio of water to sample, extraction time and extraction temperature, respectively. Gas chromatography (GC) analysis showed that black fungus polysaccharides contained glucose, xylose, mannose and ribose. Their molar percentages were 6.8%, 34.2%, 50.7% and 8.9%, respectively. FT-IR and NMR analysis showed typical chemical structure of black fungus polysaccharides. In animal experiment, high fat diet feeding for 29 days markedly reduced myocardium and blood antioxidant enzyme activities and enhanced lipid peroxidation level. Administration of black fungus polysaccharides had significantly enhanced myocardium and blood antioxidant enzyme activities and reduced lipid peroxidation level in high fat mice. Our results indicated that black fungus polysaccharides could be beneficial for protection against cardiovascular diseases and its complications. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：1061 / 1068

页数：8

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