Study on antimicrobial activity of chitosan with different molecular weights

被引:978
作者
Zheng, LY [1 ]
Zhu, JAF [1 ]
机构
[1] Zhejiang Univ, Dept Chem & Biochem Engn, Hangzhou 310027, Peoples R China
基金
中国国家自然科学基金;
关键词
chitosan; antimicrobial activity; molecular weight; E; coli; Staphylococcus aureus;
D O I
10.1016/j.carbpol.2003.07.009
中图分类号
O69 [应用化学];
学科分类号
081704 [应用化学];
摘要
E. coli and Staphylococcus aureus are used to study the antimicrobial activity of chitosan of different molecular weights (MW). The effect of the concentration and MW of chitosan were investigated, respectively, and the antimicrobial mechanism was discussed. For chitosan with MW below 300 kDa, the antimicrobial effect on S. aureus was strengthened as the MW increased. In contrast, the effect on E. coli was weakened. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:527 / 530
页数:4
相关论文
共 13 条
[1]
In vitro antimicrobial activity of a chitooligosaccharide mixture against Actinobacillus actinomycetemcomitans and Streptococcus mutans [J].
Choi, BK ;
Kim, KY ;
Yoo, YJ ;
Oh, SJ ;
Choi, JH ;
Kim, CY .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2001, 18 (06) :553-557
[2]
GUAN Y, 1997, APPL EXPLORE, V2, P35
[3]
Chitosan disrupts the barrier properties of the outer membrane of Gram-negative bacteria [J].
Helander, IM ;
Nurmiaho-Lassila, EL ;
Ahvenainen, R ;
Rhoades, J ;
Roller, S .
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2001, 71 (2-3) :235-244
[4]
Antimicrobial effect of chitooligosaccharides produced by bioreactor [J].
Jeon, YJ ;
Park, PJ ;
Kim, SK .
CARBOHYDRATE POLYMERS, 2001, 44 (01) :71-76
[5]
Production of chitooligosaccharides using an ultrafiltration membrane reactor and their antibacterial activity [J].
Jeon, YJ ;
Kim, SK .
CARBOHYDRATE POLYMERS, 2000, 41 (02) :133-141
[6]
Synthesis and antibacterial activities of quaternary ammonium salt of chitosan [J].
Jia, ZS ;
Shen, DF ;
Xu, WL .
CARBOHYDRATE RESEARCH, 2001, 333 (01) :1-6
[7]
JIANG YY, 1997, APPL EXPLORE, V2, P22
[8]
A new lipid emulsion formulation with high antimicrobial efficacy using chitosan [J].
Jumaa, M ;
Furkert, FH ;
Müller, BW .
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2002, 53 (01) :115-123
[9]
KYOON NH, 2002, INT J FOOD MICROBIOL, V74, P65
[10]
The antifungal properties of chitosan in laboratory media and apple juice [J].
Roller, S ;
Covill, N .
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 1999, 47 (1-2) :67-77