Synthesis, characterization and chemisorption on gold of a β-cyclodextrin-lipoic acid conjugate

被引：15

作者：

Carofiglio, T

Fornasier, R

Jicsinszky, L

Tonellato, U

Turco, C

机构：

[1] Univ Padua, Dipartimento Chim Inorgan Metallorgan & Anali, I-35100 Padua, Italy

[2] Univ Padua, CNR, Ctr Meccanismi Reazioni Organ, Dipartimento Chim Organ, I-35100 Padua, Italy

[3] Cyclolab R&D Lab, H-1117 Budapest, Hungary

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 31期

关键词：

D O I：

10.1016/S0040-4039(01)01001-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Mono-6-lipoyl-amido-2,3,6-O-permethyl-beta -cyclodextrin, TM beta CDLA, was synthesized in 79% isolated yield by coupling the mono-6-amino-permethyl-beta -cyclodextrin with lipoic acid in the presence of 1-(3-dimethylamino)ethyl carbodiimide. The identity of cyclodextrin-lipoic acid conjugate was confirmed by NMR spectroscopy and electrospray mass spectrometry. Chemiadsorption of TM beta CDLA on colloidal gold was shown to occur by colloid flocculation test analysis. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：5241 / 5244

页数：4

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