DNA microarrays in parasitology: strengths and limitations

被引：20

作者：

Boothroyd, JC ^{[1
]}

Blader, I

Cleary, M

Singh, U

机构：

[1] Stanford Univ, Sch Med, Dept Microbiol & Immunol, Stanford, CA 94305 USA

[2] Univ Oklahoma, Hlth Sci Ctr, Dept Microbiol & Immunol, Oklahoma City, OK 73190 USA

[3] Stanford Univ, Sch Med, Dept Med, Div Infect Dis, Stanford, CA 94305 USA

来源：

TRENDS IN PARASITOLOGY | 2003年 / 19卷 / 10期

关键词：

D O I：

10.1016/j.pt.2003.08.002

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Genome sequencing efforts have provided a wealth of new biological information that promises to have a major impact on our understanding of parasites. Microarrays provide one of the major high-throughput platforms by which this information can be exploited in the laboratory. Many excellent reviews and technique articles have recently been published on applying microarrays to organisms for which fully annotated genomes are at hand. However, many parasitologists work on organisms whose genomes have been only partially sequenced and where little, if any, annotation is available. The focus of this review is on how to use and apply microarrays to these situations.

引用

页码：470 / 476

页数：7

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