Developing processes for crystallization-induced asymmetric transformation

被引：76

作者：

Anderson, NG ^{[1
]}

机构：

[1] Andersons Proc Solut, Jacksonville, OR 97530 USA

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2005年 / 9卷 / 06期

关键词：

D O I：

10.1021/op050119y

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Crystallization-induced dynamic resolution (CIDR) is an adaptation of dynamic resolution, a process that can afford in principle a quantitative yield of chiral product from a racemic starting material through in situ resolution. Crystallization-induced asymmetric transformation (CIAT) includes CID R and the preparation of diastereomers and olefins that are driven by crystallization. The history of CIAT and CIDR processes is reviewed, along with key observations made by researchers. Recommendations are made for identifying opportunities for and developing CIAT processes.

引用

页码：800 / 813

页数：14

共 138 条

[1] Conversion of the laboratory synthetic route of the N-aryl-2-benzothiazolamine R116010 to a manufacturing method
Aelterman, W
Lang, Y
Willemsens, B
Vervest, I
Leurs, S
De Knaep, F
[J]. ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2001, 5 (05) : 467 - 471
[2] Synthesis of N-benzyl-3-(S)-(+)-(4-fluorophenyl)-1,4-oxazin-2-one via a crystallisation induced asymmetric transformation
Alabaster, RJ
Gibson, AW
Johnson, SA
Edwards, JS
Cottrell, IF
[J]. TETRAHEDRON-ASYMMETRY, 1997, 8 (03) : 447 - 450
[3] Amat M, 2002, ANGEW CHEM INT EDIT, V41, P335, DOI 10.1002/1521-3773(20020118)41:2<335::AID-ANIE335>3.0.CO
[4] 2-Y
[5] Amos J. G., 1999, US Patents, Patent No. [6001996, 6,001,996]
[6] Assessing the benefits of direct isolation processes
Anderson, NG
[J]. ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2004, 8 (02) : 260 - 265
[7] Quantification and optimization of dynamic kinetic resolution
Andraos, J
[J]. JOURNAL OF PHYSICAL CHEMISTRY A, 2003, 107 (13) : 2374 - 2387
[8] AN EFFICIENT ASYMMETRIC-SYNTHESIS OF (R)-3-AMINO-2,3,4,5-TETRAHYDRO-1H-[1]BENZAZEPIN-2-ONE
ARMSTRONG, JD
ENG, KK
KELLER, JL
PURICK, RM
HARTNER, FW
CHOI, WB
ASKIN, D
VOLANTE, RP
[J]. TETRAHEDRON LETTERS, 1994, 35 (20) : 3239 - 3242
[9] ARMSTRONG VW, 1978, TETRAHEDRON LETT, V19, P4311
[10] Synthesis of enantioenriched axially chiral anilides from atropisomerically enriched tartarate ortho-anilides
Ates, A
Curran, DP
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (21) : 5130 - 5131

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