High-intensity aerobic exercise improves diastolic function in coronary artery disease

被引：66

作者：

Amundsen, Brage H. ^{[1
,2
]}

Rognmo, Oivind ^{[2
]}

Hatlen-Rebhan, Gudrun ^{[2
]}

Slordahl, Stig A. ^{[1
,2
]}

机构：

[1] Norwegian Univ Sci & Technol, Dept Circulat & Med Imaging, N-7034 Trondheim, Norway

[2] Univ Trondheim Hosp, Dept Cardiol, St Olavs Hosp, Trondheim, Norway

来源：

SCANDINAVIAN CARDIOVASCULAR JOURNAL | 2008年 / 42卷 / 02期

关键词：

clinical trial; exercise therapy; tissue Doppler imaging; exercise intensity; strain rate; heart; echocardiography;

D O I：

10.1080/14017430701744477

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective. To study the effect of aerobic treadmill exercise training with different intensity on left ventricular (LV) function in patients with stable coronary artery disease, using Strain Rate- and Tissue Doppler Imaging. Design. Seventeen patients were randomly assigned to either moderate (50-60% of peak oxygen uptake (VO2peak)) or high intensity exercise (80-90% of VO2peak) for 10 weeks. Results. The increase of VO2peak was significantly higher (p=0.01) in the high intensity group (17 vs. 8%). Mean LV early diastolic strain rate increased in the high, but not in the moderate, intensity group. For systolic strain rate or mitral annular velocities there were no change after training in either group. Conclusions. Aerobic treadmill exercise improves early diastolic relaxation in patients with stable coronary artery disease, measured by the mean LV early diastolic strain rate.

引用

收藏

页码：110 / 117

页数：8

相关论文

共 30 条

[1] Automatic timing of aortic valve closure in apical tissue Doppler images [J].

Aase, SA ;

Stoylen, A ;

Ingul, CB ;

Frigstad, S ;

Torp, H .

ULTRASOUND IN MEDICINE AND BIOLOGY, 2006, 32 (01) :19-27

[2] Skeletal muscle and cardiovascular adaptations to exercise conditioning in older coronary patients [J].

Ades, PA ;

Waldmann, ML ;

Meyer, WL ;

Brown, KA ;

Poehlman, ET ;

Pendlebury, WW ;

Leslie, KO ;

Gray, PR ;

Lew, RR ;

LeWinter, MM .

CIRCULATION, 1996, 94 (03) :323-330

[3] STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT [J].

BLAND, JM ;

ALTMAN, DG .

LANCET, 1986, 1 (8476) :307-310

[4] COMBINED INFLUENCE OF VENTRICULAR LOADING AND RELAXATION ON THE TRANSMITRAL FLOW VELOCITY PROFILE IN DOGS MEASURED BY DOPPLER ECHOCARDIOGRAPHY [J].

CHOONG, CY ;

ABASCAL, VM ;

THOMAS, JD ;

GUERRERO, JL ;

MCGLEW, S ;

WEYMAN, AE .

CIRCULATION, 1988, 78 (03) :672-683

[5] Effect of high intensity exercise training on central hemodynamic responses to exercise in men with reduced left ventricular function [J].

Dubach, P ;

Myers, J ;

Dziekan, G ;

Goebbels, U ;

Reinhart, W ;

Muller, P ;

Buser, P ;

Stulz, P ;

Vogt, P ;

Ratti, R .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 29 (07) :1591-1598

[6] IMPROVEMENT OF LEFT-VENTRICULAR CONTRACTILE FUNCTION BY EXERCISE TRAINING IN PATIENTS WITH CORONARY-ARTERY DISEASE [J].

EHSANI, AA ;

BIELLO, DR ;

SCHULTZ, J ;

SOBEL, BE ;

HOLLOSZY, JO .

CIRCULATION, 1986, 74 (02) :350-358

[7] A RANDOMIZED TRIAL OF EXERCISE TRAINING IN PATIENTS WITH CORONARY HEART-DISEASE [J].

FROELICHER, V ;

JENSEN, D ;

GENTER, F ;

SULLIVAN, M ;

MCKIRNAN, MD ;

WITZTUM, K ;

SCHARF, J ;

STRONG, ML ;

ASHBURN, W .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1984, 252 (10) :1291-1297

[8]

GLEDHILL N, 1994, MED SCI SPORT EXER, V26, P1116

[9] Automated analysis of strain rate and strain: Feasibility and clinical implications [J].

Ingul, CB ;

Torp, H ;

Aase, SA ;

Berg, S ;

Stoylen, A ;

Slordahl, SA .

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2005, 18 (05) :411-418

[10] Moderate vs. high exercise intensity: Differential effects on aerobic fitness, cardiomyocyte contractility, and endothelial function [J].

Kemi, OJ ;

Haram, PM ;

Loennechen, JP ;

Osnes, JB ;

Skomedal, T ;

Wisloff, U ;

Ellingsen, O .

CARDIOVASCULAR RESEARCH, 2005, 67 (01) :161-172