Use of cyclobutyl derivatives as intermediates in the synthesis of 1,2a,3,8b-tetrahydro-2H-cyclobuta[c]chromenes

被引：18

作者：

Bernard, AM ^{[1
]}

Floris, C ^{[1
]}

Frongia, A ^{[1
]}

Piras, PP ^{[1
]}

Secci, F ^{[1
]}

机构：

[1] Univ Cagliari, Dipartimento Sci Chim, I-09042 Monserrato, Cagliari, Italy

来源：

TETRAHEDRON | 2004年 / 60卷 / 02期

关键词：

cyclopropanes; cyclobutanones; electrophilic aromatic substitutions; ring opening; kinetic resolution; capsorubin;

D O I：

10.1016/j.tet.2003.11.018

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from cyclobutanones and tertiary cyclobutanols several new chromenes containing a cyclobutane ring have been prepared by acid catalyzed intramolecular alkylation of an oxygen-carrying aromatic ring. Interestingly one of the cyclobutanols leads to 3-[(4-methoxyphenoxy)methyl]-2,2,3-trimethylcyclopentanone that is a precursor in the synthesis of the carotenoid pigment capsorubin. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：449 / 457

页数：9

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