Single-Walled Nanotube/Amphiphile Hybrids for Efficacious Protein Delivery: Rational Modification of Dispersing Agents

被引：35

作者：

Brahmachari, Sayanti ^{[1
]}

Das, Dibyendu ^{[1
]}

Shome, Anshupriya ^{[1
]}

Das, Prasanta Kumar ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci, Dept Biol Chem, Kolkata 700032, India

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 47期

关键词：

amphiphiles; cellular delivery; nanotubes; proteins; surfactants; CARBON NANOTUBES; FUNCTIONALIZATION; DESIGN; TRANSPORTERS; DNA;

D O I：

10.1002/anie.201105622

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Designed to deliver: Carbon nanotube (CNT)/amphiphile hybrids with remarkable stability and cell viability under biologically relevant conditions can be obtained by rational modification of the molecular structure of amphiphilic dispersing agents (see scheme; PEG= poly(ethylene glycol)). The CNT/amphiphile hybrids are dispersible in water and efficiently shuttle proteins across mammalian cell membranes. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：11243 / 11247

页数：5

共 30 条

[1] A novel tetraester construct that reduces cationic lipid-associated cytotoxicity. Implications for the onset of cytotoxicity [J].

Aberle, AM ;

Tablin, F ;

Zhu, J ;

Walker, NJ ;

Gruenert, DC ;

Nantz, MH .

BIOCHEMISTRY, 1998, 37 (18) :6533-6540

[2]

[Anonymous], 2004, ANGEW CHEM, DOI DOI 10.1002/ANGE.200460437

[3] Determination of the concentration of single-walled carbon nanotubes in aqueous dispersions using UV-visible absorption spectroscopy [J].

Attal, S. ;

Thiruvengadathan, R. ;

Regev, O. .

ANALYTICAL CHEMISTRY, 2006, 78 (23) :8098-8104

[4] Nanotube Surfactant Design: The Versatility of Water-Soluble Perylene Bisimides [J].

Backes, Claudia ;

Schmidt, Cordula D. ;

Rosenlehner, Karin ;

Hauke, Frank ;

Coleman, Jonathan N. ;

Hirsch, Andreas .

ADVANCED MATERIALS, 2010, 22 (07) :788-802

[5] High Population of Individualized SWCNTs through the Adsorption of Water-Soluble Perylenes [J].

Backes, Claudia ;

Schmidt, Cordula D. ;

Hauke, Frank ;

Boettcher, Christoph ;

Hirsch, Andreas .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (06) :2172-2184

[6] Antifungal Activity of Amphotericin B Conjugated to Carbon Nanotubes [J].

Benincasa, Monica ;

Pacor, Sabrina ;

Wu, Wei ;

Prato, Maurizio ;

Bianco, Alberto ;

Gennaro, Renato .

ACS NANO, 2011, 5 (01) :199-208

[7] Superior SWNT dispersion by amino acid based amphiphiles: designing biocompatible cationic nanohybrids [J].

Brahmachari, Sayanti ;

Das, Dibyendu ;

Das, Prasanta Kumar .

CHEMICAL COMMUNICATIONS, 2010, 46 (44) :8386-8388

[8] Functionalized Single-Walled Carbon Nanotubes as Rationally Designed Vehicles for Tumor-Targeted Drug Delivery [J].

Chen, Jingyi ;

Chen, Shuyi ;

Zhao, Xianrui ;

Kuznetsova, Larisa V. ;

Wong, Stanislaus S. ;

Ojima, Iwao .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (49) :16778-16785

[9] Enzyme-Activated Surfactants for Dispersion of Carbon Nanotubes [J].

Cousins, Brian G. ;

Das, Apurba K. ;

Sharma, Raman ;

Li, Yanning ;

McNamara, Jonathan P. ;

Hillier, Ian H. ;

Kinloch, Ian A. ;

Ulijn, Rein V. .

SMALL, 2009, 5 (05) :587-590

[10] Superior Activity of Structurally Deprived Enzyme-Carbon Nanotube Hybrids in Cationic Reverse Micelles [J].

Das, Dibyendu ;

Das, Prasanta Kumar .

LANGMUIR, 2009, 25 (08) :4421-4428

← 1 2 3 →