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Commercial Dengue Rapid Diagnostic Tests for Point-of-Care Application: Recent Evaluations and Future Needs?

被引：106
作者：
Blacksell, Stuart D. [1 ,2 ]
机构：
[1] Univ Oxford, Churchill Hosp, Nuffield Dept Clin Med, Ctr Trop Med, Oxford, England
[2] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res Unit, Bangkok 10400, Thailand
来源：
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY | 2012年
基金：
英国惠康基金;
关键词：
LINKED-IMMUNOSORBENT-ASSAY; NONSTRUCTURAL GLYCOPROTEIN NS1; IMMUNOGLOBULIN-M ANTIBODIES; VIRUS-INFECTION; IMMUNOCHROMATOGRAPHIC ASSAYS; PROTEIN NS1; HEMORRHAGIC-FEVER; ANTIGEN-DETECTION; IGG ANTIBODIES; ACCURACY;
D O I：
10.1155/2012/151967
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Dengue fever, dengue haemorrhagic fever, and dengue shock syndrome (DF/DHF/DSS) are tropical diseases that cause significant humanitarian and economic hardship. It is estimated that more than 2.5 billion people are at risk of infection and more than 100 countries have endemic dengue virus transmission. Laboratory tests are essential to provide an accurate diagnosis of dengue virus infection so that appropriate treatment and patient management may be administered. In many dengue endemic settings, laboratory diagnostic resources are limited and simple rapid diagnostic tests (RDTs) provide opportunities for point-of-care diagnosis. This paper addresses current issues relating to the application of commercial dengue RDTs for the diagnosis of acute dengue virus infection, recent diagnostic evaluations, and identifies future needs.
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页数：12
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