Organic reactions of ionic intermediates promoted by atmospheric-pressure thermal activation

被引：63

作者：

Chen, Hao ^{[1
]}

Eberlin, Livia S. ^{[1
]}

Nefliu, Marcela ^{[1
]}

Augusti, Rodinei ^{[2
]}

Cooks, R. Graham ^{[1
]}

机构：

[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA

[2] Univ Fed Minas Gerais, Dept Chem, BR-31270901 Belo Horizonte, MG, Brazil

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 18期

关键词：

green chemistry; mass spectrometry; protonation; reaction intermediates; synthetic methods;

D O I：

10.1002/anie.200800072

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) A mild-mannered process: Novel methodology, in which electrosonic spray ionization (ESSI, see schematic diagram) is used as the proton source, has been used to generate ionic reaction intermediates whose conversion into products can be promoted by atmospheric-pressure thermal activation. Reactions performed under these mild conditions include Borsche-Drechsel cyclization, Fischer indole synthesis, and pinacol rearrangement. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3422 / 3425

页数：4

共 36 条

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