Genetic dissection of glucocorticoid receptor function in mice

被引：153

作者：

Tronche, F ^{[1
]}

Kellendonk, C ^{[1
]}

Reichardt, HM ^{[1
]}

Schütz, G ^{[1
]}

机构：

[1] Deutsch Krebsforschungszentrum, D-69120 Heidelberg, Germany

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1998年 / 8卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(98)80007-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Upon hormone binding, the activated glucocorticoid receptor (GR) functions as a transcription factor via different modes of action to control gene expression. Recent gene-targeting studies in mice provide new insight into the role of GR in vivo and are helping decipher the molecular mechanisms underlying its actions.

引用

页码：532 / 538

页数：7

共 49 条

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