Sequences in influenza A virus PB2 protein that determine productive infection for an avian influenza virus in mouse and human cell lines

被引：35

作者：

Yao, YX

Mingay, LJ

McCauley, JW

Barclay, WS

机构：

[1] Univ Reading, Sch Anim & Microbial Sci, Reading RG6 6AJ, Berks, England

[2] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

[3] Inst Anim Hlth, Compton Lab, Newbury RG20 7NN, Berks, England

来源：

JOURNAL OF VIROLOGY | 2001年 / 75卷 / 11期

关键词：

D O I：

10.1128/JVI.75.11.5410-5415.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Reverse genetics was used to analyze the host range of two avian influenza viruses which differ in their ability to replicate in mouse and human cells in culture, Engineered viruses carrying sequences encoding amino acids 362 to 581 of PB2 from a host range variant productively infect mouse and human cells.

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收藏

页码：5410 / 5415

页数：6

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