Synthesis of quinoxalines by cyclization of α-arylimino oximes of α-dicarbonyl compounds

被引：74

作者：

Xekoukoulotakis, NP ^{[1
]}

Hadjiantoniou-Maroulis, CP ^{[1
]}

Maroulis, AJ ^{[1
]}

机构：

[1] Aristotelian Univ Salonika, Dept Chem, GR-54006 Salonika, Greece

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 52期

关键词：

alpha-arylimino oximes; iminyl radical; quinoxalines; spirodienyl radical;

D O I：

10.1016/S0040-4039(00)01847-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Heating the title compounds 1 at reflux in acetic anhydride yields quinoxalines 3 and 4 via a presumed aryliminoiminyl radical 5, resulting from homolytic cleavage of the N-O bond in the intermediate ester 2. The observed regioselectivity of the reaction is also rationalized by implicating such a radical. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：10299 / 10302

页数：4

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