Diabetic gastroparesis-Backwards and forwards

被引：29

作者：

Chang, Jessica ^{[1
,2
]}

Rayner, Christopher K. ^{[1
,2
]}

Jones, Karen L. ^{[1
,2
]}

Horowitz, Michael ^{[1
,2
]}

机构：

[1] Univ Adelaide, Discipline Med, Royal Adelaide Hosp, Adelaide, SA 5000, Australia

[2] Ctr Clin Res Excellence Nutr Physiol Intervent &, Adelaide, SA, Australia

来源：

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2011年 / 26卷

关键词：

blood glucose; diabetes; gastric emptying; incretin hormones; GLUCAGON-LIKE PEPTIDE-1; GASTRIC ELECTRICAL-STIMULATION; INTESTINAL GLUCOSE DELIVERY; POSTPRANDIAL PLASMA-GLUCOSE; HEALTHY-SUBJECTS; BOTULINUM-TOXIN; GASTROINTESTINAL SYMPTOMS; INTERSTITIAL-CELLS; BLOOD-GLUCOSE; AMYLIN ANALOG;

D O I：

10.1111/j.1440-1746.2010.06573.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Diabetic gastroparesis was once thought to be rare, associated with a poor prognosis, and to affect only patients with type 1 diabetes and irreversible autonomic neuropathy. A landmark study conducted by Horowitz et al. and published in JGH in 1986 paved the way for further studies to examine the pathophysiology, natural history and prognosis of diabetic gastroparesis, as well as its optimal management. This review summarizes the developments in knowledge gained over the last similar to 25 years that have led to understanding about normal and disordered gastric emptying in diabetes, with a particular emphasis on the inter-relationship between the rate of gastric emptying and the regulation of blood glucose.

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收藏

页码：46 / 57

页数：12

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