The incidence of obesity has reached epidemic proportions within industrial societies; however, research on human obesity has been hampered by our inability to control genetic and environmental factors. The control of energy homeostasis appears to be conserved among species. Recent creative research in Caenorhabditis elegans, including the application of a genome-wide RNA interference analysis, has provided insight into the genes involved in energy balance. In this article, we discuss the results of these studies and their potential importance to humans.
机构:
Columbia Univ, Coll Phys & Surg, Naomi Berrie Diabet Ctr, Dept Med, New York, NY 10032 USAColumbia Univ, Coll Phys & Surg, Naomi Berrie Diabet Ctr, Dept Med, New York, NY 10032 USA
Kitamura, T
;
Kahn, CR
论文数: 0引用数: 0
h-index: 0
机构:Columbia Univ, Coll Phys & Surg, Naomi Berrie Diabet Ctr, Dept Med, New York, NY 10032 USA
Kahn, CR
;
Accili, E
论文数: 0引用数: 0
h-index: 0
机构:Columbia Univ, Coll Phys & Surg, Naomi Berrie Diabet Ctr, Dept Med, New York, NY 10032 USA
机构:
Columbia Univ, Coll Phys & Surg, Naomi Berrie Diabet Ctr, Dept Med, New York, NY 10032 USAColumbia Univ, Coll Phys & Surg, Naomi Berrie Diabet Ctr, Dept Med, New York, NY 10032 USA
Kitamura, T
;
Kahn, CR
论文数: 0引用数: 0
h-index: 0
机构:Columbia Univ, Coll Phys & Surg, Naomi Berrie Diabet Ctr, Dept Med, New York, NY 10032 USA
Kahn, CR
;
Accili, E
论文数: 0引用数: 0
h-index: 0
机构:Columbia Univ, Coll Phys & Surg, Naomi Berrie Diabet Ctr, Dept Med, New York, NY 10032 USA