Legionella spp. and Legionnaires' disease

被引：304

作者：

Diederen, B. M. W. ^{[1
]}

机构：

[1] Reg Publ Hlth Lab Haarlem, NL-2035 RC Haarlem, Netherlands

来源：

JOURNAL OF INFECTION | 2008年 / 56卷 / 01期

关键词：

Legionella; Legionella pneumophila; diagnosis; review; treatment; Legionnaires' disease;

D O I：

10.1016/j.jinf.2007.09.010

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Infection with Legionella spp. is an important cause of community- and hospital-acquired pneumonia, occurring both sporadically and in outbreaks. Infection with Legionella spp. ranks among the three most common causes of severe pneumonia in the community setting, and is isolated in 1-40% of cases of hospitat-acquired pneumonia. There are no clinical features unique to Legionnaires' disease. Macrolides and fluoroquinotones are the most widely used drugs in treatment. The availability of a good diagnostic repertoire, suitable for accurately diagnosing LD, constitutes the basis for the early recognition and treatment of the individual patient as well as for effective measures for prevention and control. This review summarizes the available information regarding the microbiology, clinical presentation, diagnosis and treatment of LD, with an emphasis on the laboratory diagnosis of infection with Legionella spp. (C) 2007 The British Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：1 / 12

页数：12

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