Non-N-methyl-D-aspartate receptors may mediate the transmission of emetic signals between visceral vagal afferents and the solitary nucleus in dogs

被引：13

作者：

Furukawa, N ^{[1
]}

Hatano, M ^{[1
]}

Fukuda, H ^{[1
]}

Koga, T ^{[1
]}

机构：

[1] Kawasaki Med Sch, Dept Physiol, Kurashiki, Okayama 7010192, Japan

来源：

NEUROSCIENCE LETTERS | 1998年 / 258卷 / 01期

关键词：

retching; salivary secretion; N-methyl-D-aspartate receptor; non-NMDA receptor; vagal afferents; solitary nucleus; vago-salivary reflex;

D O I：

10.1016/S0304-3940(98)00859-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

The effects of the N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists MK-801 and NBQX, respectively, on salivary secretion and retching induced by vagal stimulation were studied in decerebrate dogs. Vagal stimulation induced an increase in salivary secretion and fictive retching. Intra-4th ventricular application of vehicle or MK-801 did not change either response, while NBQX completely abolished both responses. These results suggest that non-NMDA receptors mediate both responses in the solitary nucleus. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：53 / 56

页数：4

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