Quantitative evidence for multiple widespread representations of individual muscles in the cat motor cortex

被引:21
作者
Schneider, C
Zytnicki, D
Capaday, C
机构
[1] Univ Laval, Dept Anat & Physiol, Brain & Movement Lab, CRULRG,Hop Robert Giffard, Quebec City, PQ G1J 2G3, Canada
[2] Univ Paris 05, CNRS, FRE 2361, F-75270 Paris, France
基金
加拿大健康研究院; 加拿大自然科学与工程研究理事会;
关键词
motor cortex map; microstimulation; corticospinal neurons; evoked motor potentials;
D O I
10.1016/S0304-3940(01)02105-X
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We sought to determine why a given muscle appears represented in widespread loci in the motor cortex (MCx). To th is end, we microstimulated every 500 mum along medio-lateral rows and recorded the evoked electromyographic (EMG) responses of up to a dozen forelimb muscles of the cat. A consistent finding in all animals studied was that along a given row, distal muscle responses could be elicited from medially situated cortical loci and conversely, proximal muscles responses from laterally situated cortical loci. In many such cases, the evoked EMG responses were such that the largest responses from a distal muscle were obtained by stimulation ata medially situated point and those of a proximal muscle from a laterally situated point. A Spearman correlation analysis showed that there was no correlation between cortical position and where the peak response of a given muscle occurred. These quantitative results strongly support the view that in the forelimb area of the cat MCx there exists widespread 'colonies' of corticospinal neurons with common spinal cord targets. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:183 / 187
页数:5
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