Virus isolation for diagnosing dengue virus infections in returning travelers

被引:5
作者
Teichmann, D
Göbels, K
Niedrig, M
Sim-Brandenburg, JW
Làge-Stehr, J
Grobusch, MP
机构
[1] Stadt Klinikum Dresden Neustadt, Med Clin, Dept Trop Med & Infect Dis, D-01129 Dresden, Germany
[2] Humboldt Univ, Med Clin, Dept Infect Dis, D-13353 Berlin, Germany
[3] Robert Koch Inst, D-13353 Berlin, Germany
关键词
D O I
10.1007/s10096-003-1004-5
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Dengue fever is recognized as one of the most frequent imported acute febrile illnesses affecting European tourists returning from the tropics. In order to assess the value of virus isolation for the diagnosis of dengue fever, 70 cases of dengue fever confirmed in German travelers during the period 1993-2001 were analyzed retrospectively. In 26 patients who had developed acute febrile illness within 2 weeks following their return from a trip to a dengue-endemic area, 9 of 13 attempts to isolate the virus were successful in sera drawn 1-5 days and 2 of 13 sera drawn 6-10 days after the onset of illness. DEN-1 was the most frequent serotype isolated. If performed early, virus isolation is a reliable tool for detecting dengue virus in returning travelers.
引用
收藏
页码:697 / 700
页数:4
相关论文
共 21 条
[1]   Dengue haemorrhagic fever: questions of pathogenesis [J].
Cardosa, MJ .
CURRENT OPINION IN INFECTIOUS DISEASES, 2000, 13 (05) :471-475
[2]   Seroprevalence of dengue, Chikungunya and Sindbis virus infections in German aid workers [J].
Eisenhut, M ;
Schwarz, TF ;
Hegenscheid, B .
INFECTION, 1999, 27 (02) :82-85
[3]   The global emergence/resurgence of arboviral diseases as public health problems [J].
Gubler, DJ .
ARCHIVES OF MEDICAL RESEARCH, 2002, 33 (04) :330-342
[4]   Dengue:: an update [J].
Guzmán, MG ;
Kouri, G .
LANCET INFECTIOUS DISEASES, 2002, 2 (01) :33-42
[5]   LABORATORY-SCALE PRODUCTION OF MONOCLONAL-ANTIBODIES IN A TUMBLING CHAMBER [J].
JASPERT, R ;
GESKE, T ;
TEICHMANN, A ;
KASSNER, YM ;
KRETZSCHMAR, K ;
LAGESTEHR, J .
JOURNAL OF IMMUNOLOGICAL METHODS, 1995, 178 (01) :77-87
[6]   Epidemiology and clinical features of imported dengue fever in Europe:: Sentinel surveillance data from TropNetEurop [J].
Jelinek, T ;
Müberger, NM ;
Harms, G ;
Corachán, M ;
Grobusch, MP ;
Knobloch, J ;
Bronner, U ;
Laferl, H ;
Kapaun, A ;
Bisoffi, Z ;
Clerinx, J ;
Puente, S ;
Fry, G ;
Schulze, M ;
Hellgren, U ;
Gjorup, I ;
Chalupa, P ;
Hatz, C ;
Matteelli, A ;
Schmid, M ;
Nielsen, LN ;
da Cunha, S ;
Atouguia, J ;
Myrvang, B ;
Fleischer, K .
CLINICAL INFECTIOUS DISEASES, 2002, 35 (09) :1047-1052
[7]   Dengue fever in international travelers [J].
Jelinek, T .
CLINICAL INFECTIOUS DISEASES, 2000, 31 (01) :144-147
[8]   Dengue virus structural differences that correlate with pathogenesis [J].
Leitmeyer, KC ;
Vaughn, DW ;
Watts, DM ;
Salas, R ;
de Chacon, IV ;
Ramos, C ;
Rico-Hesse, R .
JOURNAL OF VIROLOGY, 1999, 73 (06) :4738-4747
[9]  
NIEDRIG M, 1998, EUROSURVEILLANCE, V3, P80
[10]  
Reinhardt B, 1998, J MED VIROL, V56, P159, DOI 10.1002/(SICI)1096-9071(199810)56:2&lt