Tumor escape from immune response: Mechanisms and targets of activity

被引：63

作者：

Gabrilovich, D

Pisarev, V

机构：

[1] Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33612 USA

[2] Univ Nebraska, Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA

来源：

CURRENT DRUG TARGETS | 2003年 / 4卷 / 07期

关键词：

D O I：

10.2174/1389450033490849

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Immune system plays an important role in control of tumor progression. Effective antitumor immune response depends on close interaction of several elements of immune system. They include antigen-presenting cells, different subsets of T cells, B cells and NK cells. However, tumor cells developed a number of mechanisms to escape recognition and elimination by immune system. In this review we will discuss these mechanisms and address possible approaches to correct them.

引用

页码：525 / 536

页数：12

共 204 条

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